Bioinformatics of pathogenic food bacteria

Abstract

Cholera is a fatal water borne disease caused by Vibrio cholerae. The primary symptoms include profuse watery diarrhea, muscle cramps and vomiting of clear fluid leading to rapid dehydration and electrolyte imbalance. and death in some cases. The causal organism i.e. Vibrio cholerae was first isolated by an Italian anatomist. Filippo Pacini in 1854. With the advent of genome sequencing technology, several Vibrio cholerae strains have been sequenced and available in public domain. This provided the opportunity for the scientists to study their genome in details. In the present review we have looked into the genetics of food pathogen as a whole, with special reference to research on V. cholerae. We have also critically reviewed various aspects of Bioinformatics like codon usage patterns, phylogenetic studies, studies on structural bioinformatics etc. on food borne bacteria. We are confident that the present review will help the researchers of food pathogenic biology to obtain valuable information about the present status of bioinformatics of food pathogenic bacteria and future outlook of these aspects.