Please use this identifier to cite or link to this item:
http://ir.nbu.ac.in/handle/123456789/4429
Title: | DNA and its bending: a glimpse of mechanism and implication in bacteriology |
Other Titles: | NBU Journal of Plant Sciences, Vol.4, (March 2010) p 57-63 |
Authors: | Mukherjee, Sayani Dam, Bomba Sen, Sukannta K |
Keywords: | Bacteria Supercoiling; Heteronumous Cancer therapy |
Issue Date: | Mar-2010 |
Publisher: | University of North Bengal |
Abstract: | The doub le hdkol DN A s lrurturc vorlcs from one s pecie., to oth er. Donel DNA Is nl so ovn llnblc In the cell. Bending is c.xprcs$c<l by the supcrcolling of DNA s1ruc111rc. The mcc l1111ilsm of DNA bending Is brl.'led on two hnsk models: th e A-Trnct model where th e phnslng o f 6/J\ residues nrc lm po rtnnt nnd In -Jun cti o n bending modd. where lhe hc1cro ny111ous poly (dA), poly (dT) nnd B-DNA Juncll on nrc res po nsibl e fo r causing bcn,I i n the hell:\ nxi s. DNA bend ing hos scvcrul impli c111lons, like tronscrlption, rcpll cntion, rcgulntil1 n etc., 1hnt ind uce th e protein• protein nnd protein-DNA in1crnc1lo n. Thi s DNA bend ing mechanis m with multidimens ional 011ribu1cs has importnnt npplicotlons such os dru g prcporoti o n. cance r thempy nnd so 011 . |
URI: | http://ir.nbu.ac.in/handle/123456789/4429 |
ISSN: | 0974-6927 |
Appears in Collections: | NBU Journal of Plant Sciences, Vol.04, (March 2010) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
NBU Journal of Plant Sciences, Vol. 4, March 2010_10.pdf | DNA and its bending: a glimpse of mechanism and implication in bacteriology | 745.06 kB | Adobe PDF | View/Open |
Items in NBU-IR are protected by copyright, with all rights reserved, unless otherwise indicated.