University Publications

Permanent URI for this communityhttps://ir.nbu.ac.in/handle/123456789/2863

Browse

Filters

2013 - 20152

Advanced Search

Filter by

Settings

Author: search.filters.author.Jha, D.K.Has files: Yes

Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    ItemOpen Access
    Bioprospecting for microbial endophytes and their natural products
    (University of North Bengal, 2015-03) Jha, D.K.
    Endophytes are microorganisms that reside asymptomatically in internal tissues of all higher plants. There is growing interest amongst the researches about this group of organisms because these are promising sources of biologically active agents. They are potential sources of novel natural products for scope of utilization in the pharmaceutical industry, agriculture, and in environmental applications. Many researches have proven that endophyte in new and potential source of novel natural products for exploitation in modern medicine, agriculture and industry. So far, a great number of novel natural products possessing antimicrobial activities have been isolated from endophytes. It is believed that screening for antimicrobial compounds from endophytes is a promising way to overcome the increasing threat of drug resistant strains of human and plant pathogen. Antimicrobial metabolites isolated from endophytes belong to diverse structural classes, including: alkaloids, peptides, steroids, terpenoids, phenols, quinones, and flavonoids. These would provide the opportunity to utilize endophytes as a new source for production of antibiotics.
  • Thumbnail Image
    ItemOpen Access
    Screening of zinc resistant bacteria isolated from coal mine overburden soil
    (University of North Bengal, 2013-03) Tapadar, S.A.; Jha, D.K.
    Heavy metal pollution of coal mine spoils is a significant environmental problem affecting both flora and fauna. These degraded soils can be remediated by using heavy metal resistant microorganisms. Zinc has been usually reported in high concentration from coal mine spoils. The present study, therefore, deals with screening of Zinc, resistant bacteria isolated from coal mine spoils. The bacterial isolates were isolated from coal mine spoils of Tinsukia district of Assam. For the isolation of bacteria, King's B Medium and Pikovskaya's Agar Media were used. Heavy metal resistance of the bacterial isolates against zinc was tested on nutrient agar and sucrose-minimal salt low phosphate (SLP) medium. The results showed that out of the 20 test isolates 11 isolates were resistant. The minimum inhibitory concentration (MIC) ranged from 0.001 M to 0.02 M. Antibiotic resistance was studied for two most resistant isolates. The optimal growth conditions with reference to pH and temperature of the two most resistant bacterial isolates were evaluated. Growth pattern of the most resistant isolates was determined in different concentrations of zinc amended broth media. On the basis of cultural and biochemical characters, the resistant isolates were identified as Pseudomonas sp, Bacillus sp and Rhizobium sp. Some of these isolates also exhibited plant growth promoting (PGP) traits and phosphate solubilizing ability.