Browsing by Subject "Phytochemical"

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    Assessment of Therapeutic Potential and Phytochemical Profiling in Different Solvent Extracts of Centella asiatica
    (University of North Bengal, 2023) Saran Kumar Gupta
    Centella asiatica (L.) Urban, commonly known as Indian pennywort, a small perennial herb from the Apiaceae family has been used in traditional medicine for thousands of years. This study aimed to evaluate the effect of different extraction solvents on the therapeutic and phytochemical profiles of various parts of Centella asiatica. Among the various plant parts assessed, the leaves exhibited the best antioxidant and in vitro antidiabetic activity and the highest amount of phytoconstituents compared to petiole and root. Methanol was identified as the most effective solvent, yielding optimal IC50 values for DPPH (30.65 μg/ml) and ABTS (45.23 μg/ml). Additionally, the methanolic extract of leaves exhibited highest content of phenolics (65.49 mg GAE/g DW) and flavonoids (12.56 mg QE/g DW). The methanolic leaf extract also demonstrated a promising inhibition potential against α-amylase and α-glucosidase enzymes and possessed elevated levels of alkaloids, glycosides, tannins and terpenoids. This study demonstrated significant variations in the therapeutic potential of Centella asiatica, attributed to differences in the nature of the extraction solvents.
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    Pharmacological Activity of Citrus macroptera: an overview of a medicinal plant
    (University of North Bengal, 2019-03) Lala, Mousikha; Bhattachary, Malay; Sen, Arnab
    Plants and plant parts have been extensively used as medicine from the dates of early civilization. They are low in cost and have least side effects. In India, the practice of the traditional medicinal can be traced back to 5000 B.C. Citrus macroptera (Mont.) of the family Rutaceae is a bitter fruit bearing plant commonly found in tropical and subtropical regions. It is an endangered wild plant of North-eastern India. Various parts of this plant such as leaves, bark, pulp, peel specially fruits have an immense range of medicinal importance and has been used in different kinds of ailments like fever, kidney and liver dysfunction, dyspepsia, cardiovascular disease, stroke and many more to mention. The fruit of this perennial spiny plant has potential antioxidant, cytotoxic, antimicrobial, antihypertensive, antipyretic and appetite stimulant activity. The principal phytochemical constituents of this plant are Ribalinine, Edulinine, Bergamottin, Psoralen, Marmin, Severine, Geipavarine, β-pinene, α-pinene, ρ-cimene, (E)-ocimene, vanilline, Rutin, kaempferol, sabinene, limonene, γ-terpinene and so forth. Furthurmore thrombolytic, antidiabetic, antidepressant, cardioprotective, hepatoprotective activity have been reported on this plant. This review represents a comprehensive study on the various aspects of Citrus macroptera with respect to their traditional and medicinal usage or better use as alternative medicine for various kinds of treatments.